Abstract
Summary
1. A new method is described for the production of resistant bacteria by continuous exposure to an antibiotic in a liquid environment. 2. The constant-treatment technic rapidly produces streptomycin-, aureomyein-, or bacitracin-resistant variants of an isolated streptococcus, but fails to produce any significant decrease in streptococcal sensitivity to penicillin. 3. The responses of streptococci to varying degrees of exposure to streptomycin are discussed.
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