Abstract
Summary
Preparations of relaxin from the ovaries of pregnant sows and from the blood of pregnant rabbits inhibit the development of a decidual reaction in the uterus of the castrate-pseudopregnant rat following traumatization and treatment with progesterone. Partially purified relaxin samples also contain a heat-labile factor which synergizes with progesterone in the production of deciduomata. On the basis of experiments with relaxin preparations covering a wide range of specific activities, and the effects of a variety of chemical reagents, it is concluded that the inhibitory property of such preparations is a specific response to relaxin.
Get full access to this article
View all access options for this article.