Abstract
Summary
1. Fifty per cent hemolytic units of complement determined on groups of normal individuals, tuberculous patients and tuberculous patients receiving ACTH showed highest activity in the tuberculous group and least activity in the normal group. Analysis of variance showed differences between the complement activity of normal and tuberculous individuals significant. 2. A significant correlation was observed between complement levels and time after hormone administration indicating a trend toward increased complement activity (decreased 50% unit) after long continued ACTH administration. 3. A highly significant correlation was seen between the concentration of gamma globulin and complement level, increased complement activity being associated with decreased gamma globulin concentration. No correlation between complement activity and other electrophoretic components (albumin, alpha 1 and alpha 2 globulins, β globulin and fibrinogen) was observed.
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