Abstract
Summary
A highly purified preparation of pituitary growth hormone given intravenously, together with an infusion of amino acids, to 5 normal young adult men and a patient with cancer caused a consistent, rapid, sustained lowering of blood amino acid nitrogen levels and of amino acid nitrogen excretion in the urine; a rapidly occurring but transient hyperglycemia; an increase in the ketonemia of the fasting state in three subjects so studied and an increased urinary excretion of sodium-retaining material in the 2 subjects so tested. No consistent effects were noted on blood and urine phosphorus, serum alkaline phosphatase or blood eosinophiles.
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