Abstract
Summary
Experiments are described in which cells of lymphosarcoma 6-C3H-Ed implanted in Jax-C3H (He) mice, in doses which failed to induce tumors when implanted into the tail, in large doses which induced tumors that were destroyed by intermittent occlusion of the blood supply, and by regression of palpable tumors through intensive treatment with A-methopterin, led to development of immunity of the mice against subsequent progressive growth of the same tumor.
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