Abstract
Summary and conclusions
When administered intravenously to dogs anesthetized with pentobarbital, Dowanol 5OB in adequate dosage produces auricular fibrillation, but in 4 dogs was found unsuitable for use in repeated experiments on different days, since it caused respiratory depression, prolonged anesthesia, disturbances of gait, intestinal hemorrhages and death. One animal surviving a first experiment required a significantly higher single dose and higher cumulative dose for production of fibrillation during a second experiment and succumbed following the latter.
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