Abstract
Summary
1. The sera of 51 children and over 300 adults were first tested for the presence of Lansing virus neutralizing antibody. 2. Of those whose serum contained no demonstrable antibody, 6 children and 4 adults were given gamma globulin intramuscularly in doses from 0.1 to 0.4 ml per pound body weight. 3. Blood was taken at frequent intervals for 6 weeks and tested for antibody. A small quantity of antibody was present in the serum, as shown by a protective effect of the undiluted sample in mice. This antibody was detected in some cases for a few weeks. 4. No antibody was found in the serum of the same 10 persons following the oral administration of gamma globulin.
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