Abstract
Summary
A procedure for the uantitative determination of injected canine erythrocytes by a differential agglutination technic utilizing lyophilized type-specific anti-sera is described. The method was applied in a study of erythrocyte survival after transfusion of blood. Approximately 20% of the blood of the recipient dogs was withdrawn and immediately replaced with an equal volume of donor blood. Determinations were made of red cell volume, plasma volume, donor and recipient red cell counts. Serial examinations of bone marrow and peripheral leucocytes were also made. Destruction of infused cells proceeded at a rate of about one per cent per day. No changes in bone marrow morphology or peripheral leucocytes were noted. Nitrogen balance was not significantly changed.
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