Abstract
Summary
At various intervals of time following a single intravenous injection of 7-C14-anthranil-azo-ovalbumin to rabbits, the organ deposition and intracellular distribution in liver and spleen of trichloroacetic acid precipitable radioactivity was determined. The antigen was cleared rapidly from the blood and deposited in various organs, where significant amounts were retained for many months; in the initial moments of deposition, the antigen was concentrated in the microsomal proteins of liver and spleen; subsequently it was most concentrated in the mitochondrial proteins, where it remained stored indefinitely.
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