Abstract
Summary
Experiments have been reported in which the function of threonine in producting an amino acid imbalance has been investigated. The hypothesis that threonine inhibits the conversion of tryptophan to tissue pyridine nucleotides via 3-hydroxyanthranilic acid is not strongly supported by our results. the results indicate, however, that excess dietary threonine markedly interferes with the digestiion and absorption of the ration and that this is probably a better explanation for the action of excess threonine in explanation for the action of excess threonine in producing growth inhibitiion in the rat.
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