Abstract
Summary
1. The normal serum mucoprotein-tyrosine level in 55 dogs has been determined. 2. The mean value for normal dogs was found to be 2.5 mg % ± 0.11, which value corresponds closely to that for normal humans. 3. Distemper vaccine produced a temporary, but significant, elevation in the mucoprotein-tyrosine levels in dogs. 4. The peak response of the serum mucoprotein-tyrosine levels to the distemper vaccine was reached in 2 weeks; and had returned to normal in the majority of animals by 7 weeks. 5. The physiologic stress of large arteriovenous fistula loads in dogs produced a statistically significant elevation in the mucoprotein-tyrosine levels. 6. The mucoprotein-tyrosine levels were found to be elevated significantly and to a much greater degree in dogs with large arteriovenous fistulas and bacterial endocarditis produced by beta hemolytic streptococci.
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