Abstract
Summary
A subacute infection of mice with hemolytic streptococci was treated with antibiotics in such a way as to interfere to a varying degree with the persistence of the bacteria in the tissue. Striking differences w7ere noted in the subsequent susceptibility of survivors to a homologous challenge. The acquired resistance of the animals was inversely proportional to the efficacy of the treatment regimen in rapidly eliminating the infecting microorganisms in the initial infection.
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