Abstract
Summary
Except for a decrease in hematocrit volume, intravenous administration of dextran continued for 13 weeks produced in 3 normal, nonshocked dogs no demonstrable harmful effects. Blood viscosity was maintained at or above control levels when the injections were 15 to 20 ml /kg body weight. The dog receiving 10 ml/kg exhibited a tendency to adjust to the foreign polysaccharide as evidenced by a return towards normal hematocrit values and sedimentation rates in spite of continued dextran.
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