Abstract
Summary
(1) Polymyxins A, B, D and E were tested for antifungal activity against 5 species of dermatophytes and 1 systemic fungus. Varieties B and E were the most active and of equal effectiveness. (2) Activity of the polymyxins was not significantly inhibited by serum. (3) Clinical trial of the topical and systemic efficacy of polymyxins B or E in mycotic infections is suggested.
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