Abstract
Summary
Mumps virus hemolysin is inhibited by hydroxylamine hydrochloride and urethane without affecting the hemagglutinin. Cysteine increases both the hemagglutinating and hemolytic activity of mumps virus while glutathione, which has a marked, potentiating effect on the hemagglutinin, inhibits the hemolytic activity. Other reducing agents, such as hydroquinone and sodium sulfite, increase the hemagglutinating capacity of the virus. The different effects of these various substances on the hemolysin and the hemagglutinin suggest that they are distinct entities. The possibility that the hemolysin of mumps virus is a lecithinase is discussed.
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