Abstract
Summary
Growth inhibition of S. carlsbergensis, caused by choline during routine inositol assays has been described. The effect was noted at a choline to inositol molar concentration of 0.3 to 1 and maximum inhibition was reached at a ratio of 15:1. Similar inhibition occurred with dimethylamino ethanol but was not observed with ethanolamine, serine, betaine, methionine or choline phos-pholipides. For assay purposes, this inhibition was corrected for by the addition of comparable amounts of choline to the standard inositol tubes.
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