Abstract
Summary
A technic has been described for the preparation of ACTH in good yield and in potency acceptable for clinical use. Exposure of a solution of the product in 100°C for 30 minutes results in a preparation with a high degree of biological purity. Hypo-physectomized adrenalectomized rats have been employed for the bioassay of growth, thyrotrophic and gonadotrophic hormones which may contaminate ACTH.
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