Abstract
Conclusions
(1) N-(2,5-dihydroxyphenyl) pyridinium acetate inhibited the metamorphosis of tadpoles induced by thyroxine. The degree of inhibition of metamorphosis appeared proportional to the relative concentration of the drug. (2) N-(2,5-dihydroxyphenyl) pyridinium acetate, 200 mg/kg body weight, did not lower the rate of oxygen consumption of normal rats nor prevent the acceleration of oxygen consumption induced by dl-thyroxine, 2 mg/kg body weight.
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