Abstract
Summary
A series of alloxan-diabetic rats under insulin therapy was treated with ergo-tamine tartrate, Hydergine (CCK 179) and dihydroergocornine (DHO 180). The following results are recorded: Ergotamine tartrate lowered the average blood glucose value during a period of 3-10 hours after the regular 24-hour insulin injection; dihydrogenated ergot alkaloids, (dihydroergocornine or Hydergine, which is a mixture of dihydroergocornine, dihydroergokryptine and dihydroergocristine) on the other hand, seem to have little effect on the blood glucose level as regulated by insulin therapy.
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