Abstract
Summary
The quantity of acetoacetic acid produced metabolically from pyruvate, caprylate, and caproate by rat liver homogenate systems is not affected by the state of biotin nutrition of the animals. However, biotin treatment of deficient animals increased by 10-100 fold the incorporation of C14 bicarbonate into the carboxyl group of acetoacetate metabolically formed from pyruvate, caproate, caprylate or isovalerate.
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