Abstract
Conclusions
(1) Neither ACTH, cortisone, nor cortisone in conjunction with ascorbic acid appeared to have any effect on the outward course of intoxication of guinea pigs given lethal doses of diphtheria toxin. (2) Neither cortisone nor cortisone in conjunction with ascorbic acid affected the mortality of mice receiving fatal doses of either Shiga toxin or meningococci suspended in mucin. (3) Cortisone appeared to exert a protective action on the adrenals of mice receiving fatal doses of Shiga toxin and meningococci suspended in mucin, as judged by the degree of congestion.
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