Abstract
Conclusion
1. A striking change is noted in the electrophoretic pattern of the serum in nephrotic patients soon after diuresis induced by ACTH, or ACTH plus urea. The pattern which is characteristic of nephrotic serum (low albumin and large, unresolved α2. and β3. globulin peaks) reverts toward the normal after diuresis. The serum albumin rises sharply and the α2. and β3. globulin region shows clear resolution. 2. Possible explanations of these abrupt changes in the electrophoretic patterns and concentrations of serum proteins are discussed.
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