Abstract
Summary
(1) The blood and plasma volumes of guinea pigs were determined by the dilution of I131 trace iodinated rabbit globulin. (2) The average 8 to 15-minute dilution blood volume was found to be 7.53 ± 0.71 cc† per 100 g body weight, and the average plasma volume was 3.94 ± 0.37 cc† per 100 g body weight. (3) The labelled protein was found to mix slowly over a period of 20 hours into a larger body fluid volume which was found to have a minimum value of 7.58 cc/100 g body weight, which includes the peripheral plasma volume and a number of undetermined compartments.
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