Glucose-Utilization in Hepatectomized Dogs. ∗

Abstract

Summary

In 4 hepatectomized dogs the rate of disappearance of glucose from the blood during the first hour after operation was slower than during a second hour, after the intravenous injection of glucose solution. This is in contrast to previously reported findings by others that in completely eviscerated dogs there is no difference in rates of disappearance of blood-sugar before and after the administration of glucose. The findings suggest that in hepatectomized animals the intravenous injection of glucose stimulates the secretion of insulin which accelerates the rate of removal of sugar from the blood by tissues other than liver.