Preferential Incorporation of Formate Carbon into Leukemic Blood Cells as Indicated by Autoradiography. ∗

Abstract

Summary

At one hour after injection of 100,μc of C¹⁴-formate into mice with advanced Ak-4 leukemia, it has been shown by means of blood smear autoradiograms that about 90% of the leukemic cells are highly active as compared to about 5% of the more mature lymphoid elements. No active polymorphonuclears, erythrocytes, or thrombocytes were observed within one hour.