Abstract
Summary and Conclusion
(1) Changes in circulating leukocytes which occur after anaphylaxis have been compared with those after pyrogen injection. Following both of these reactions, there is immediate leukopenia followed by polymorphonuclear leukocytosis. (2) Two types of response, although superficially very similar, are distinguishable by direct eosinophil counts which reveal uniform rises with anaphylaxis and uniform falls with the pyrogenic reaction. (3) The mechanism of these hematologic changes is not touched upon in the present study. (4) It is concluded that the leukocyte changes after anaphylaxis are not due to pyrogen contamination.
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