Abstract
Summary and Conclusions
In a series of 57 sera collected from poliomyelitis patients during the acute or subacute stage of their illness, 9 (16%) gave strongly positive reactions, 5 (9%) gave questionable reactions and 43 (75%) gave negative reactions when tested for the presence of hemagglutination-inhibitory substances against Col-SK virus. All of 12 sera from patients convalescing from Jap B encephalitis gave negative reactions. In a control group of 80 sera from healthy individuals 2 (2.5%) gave positive reactions, 4 (5%) gave questionable reactions, and 74 (92.5%) gave negative reactions. Of 14 positive or questionable poliomyelitis sera, 5 contained significant neutralizing antibody levels against Col-SK virus as determined by mouse test. The significance of these findings is discussed.
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