Characteristic Electrophoretic Patterns in Hemophilia and Idiopathic Thrombocytopenia. ∗

Abstract

Summary

Characteristic electrophoretic patterns have been observed in all 5 cases of hemophilia and in all 8 cases of idiopathic thrombocytopenic purpura. These patterns show the following characteristics: (a) appearance of an unusual peak in the group of the α-globulins (α_x), and (b) disappearance of the usual α₂- and α₃-globulin peaks. The same anomaly has been observed in some cases of secondary thrombocytopenia, “anaphylactoid” type of vascular purpura, and hemolytic anemia with evidence of platelet dysfunction.