Abstract
Summary
A specific soluble substance which will combine with the nephrotoxic antibody of anti—rat kidney serum was obtained in solution. The material was liberated into solution by digesting rat kidney with trypsin at pH 8. This substance was assayed by its ability to absorb antibodies from nephrotoxic serum. It protected a total of 24 rats without failure. Control experiments excluded trypsin activity as being the protective substance. Further characterization should be possible now that this specific material has been obtained in solution.
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