Abstract
Summary
Both in vitro and in vivo experiments show that ascorbic acid exerts an inhibitory effect upon the hyaluronidase-hyaluronic acid reaction. The inhibition is more marked in the animal than in the test tube.
The components of the capillary wall and their relation to capillary permeability have been discussed.
These studies suggest that in some cases where capillary fragility is corrected by ascorbic acid, the effect could be due to the inhibitory effect of ascorbic acid upon a hyaluronidase-hyaluronic acid system, rather than to an effect of vit. C on the intercellular cement.
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