Abstract
Summary
Both pancreatic ducts were ligated in 3 dogs. Over a period of 24 hours a gradual rise of serum amylase and a moderate edema with a slight leukocytic infiltration of the interlobular connective tissue of the pancreas occurred. The pancreatic duct systems of five dogs were subjected to a pressure of 30 cm water. Serum amylase rose twice as fast as in the dogs with simple ligation. Histologically, the principal changes in the pancreas were a more intense leukocytic infiltration, including acinar areas, and degeneration of some acinar cells.
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