Abstract
Summary
A chlorguanide-resistant strain of Plasmodium gallinaceum was cross-resistant to 2,4-diamino-6,7-diphenylpteridine. The same chlorguanide-resistant strain was not cross-resistant to 2,4-diamino-5-(p-chlorophenoxy)-6-methylpyrimidine. Chlorguanide and 2,4-diamino-5-(p-chlorophenoxy)-6-methylpyrimidine were not synergistic in their antimalarial activity.
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