Abstract
Conclusions
1. The effects of both slow and relatively rapid infusion of modified human globin in 6 human subjects without renal disease were studied. No untoward effects of the infusion were noted. 2. No significant increase in urine flow over control flows was noted. There was no change in the clearances of PAH during the globin infusion as compared with the control levels. There was a slight increase in the rate of excretion of sodium during the globin infusion as compared with control levels in 2 of the 6 patients. 3. No alteration in sedimentation rate and agglutinability of red blood cells was noted as a result of the infusion of globin.
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