Abstract
Summary
In the present experiments, utilizing 1320 observations on the eyes of 44 rabbits, physostigmine, either topically or subcutaneously, did not alter the topical anesthetic activity of procaine. Subcutaneous administration of physostigmine or pilocarpine produced corneal anesthesia in the rabbit eye as measured by loss of corneal reflex. The role of cholinesterase inhibition in the penetration of non-surface anesthetics is discussed.
Get full access to this article
View all access options for this article.