Abstract
Summary
By continuous passage in the transplantable mouse tumor sarcoma 180 it has been possible to increase the ability of the virus of Russian encephalitis to destroy this tumor. Conversely, continuous passage in the mouse brain resulted in a loss of oncolytic activity. In other experiments the virus of Russian encephalitis was changed by continuous passage in the Wagnar osteogenic sarcoma so that it caused destruction of this hitherto resistant tumor.
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