Abstract
Summary
The amount of thromboplastin required for optimum prothrombin activity increases when human plasma is stored and the lost labile factor replaced. It decreases in dog plasma when the prothrombin level is reduced by means of Dicumarol or vitamin K deficiency. It is concluded that a direct relationship exists between the concentration of prothrombin and the amount of thromboplastin, for obtaining a minimal constant prothrombin time.
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