Abstract
Conclusion
1. Thiouracil produces an involution of the adrenal cortex. 2. The atrophic adrenal gland of the thiouracil-treated rat retains its sensitivity to ACTH. 3. It is suggested that the involution of the adrenal gland of the thiouracil rat is caused by a decreased ACTH secretion by the pituitary gland. This decreased ACTH level may result from the excessive TSH production in the pituitary caused by the thiouracil treatment.
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