Abstract
Summary
These studies indicate that rats on a diet containing what is considered to be an optimum vit. B complex content have the ability to produce circulating complement fixing antibodies when immunized with relatively large amounts of the rickettsiae of murine typhus fever. Likewise, rats maintained on a diet containing only one-tenth of the presumed optimum also have the ability to produce these same antibodies to approximately the same titers. Pantothenic acid and thiamin deficiencies influenced the antibody response when a relatively small amount of immunizing material was injected. The influence is not as apparent when relatively large amounts of the antigenic material was employed.
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