Abstract
Discussion and Summary
A relatively simple technic for the intraspinal inoculation of mice which lends itself to routine laboratory use has been described. For Lansing poliomyelitis virus, it seems to be a more sensitive method of detecting virus than the intracerebral technic. The quantitation of virus titers by this method is consistent between two different technicians and on repeated tests by one technician from any one set of virus dilutions. It can be applied to the routine testing of serums for Lansing antibodies. The chief advantage of the technic is the marked shortening of the incubation period of Lansing infection in mice as com-1 pared to that following intracerebral inoculation.
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