Toxicity of Glycine for Vitamin B 12 -Deficient Chicks. ∗ †

Abstract

Summary

The plasma levels for nonprotein nitrogen and amino nitrogen after administration of glycine were higher in vit. B₁₂-deficient chicks than in B₁₂-injected chicks. One gram of glycine, when force fed in gelatin capsules, was toxic to starved, B₁₂-deficient chicks and less toxic to B12-deficient chicks which had not been starved. Chicks which had been injected with vit. B₁₂ were able to withstand the glycine whether or not they had been without food.