Abstract
Summary
Male rats were eviscerated and eviscerated-adrenalectomized. All of the animals received continuous intravenous infusions of saline with glucose and insulin for 24 and 48 hours. The administration of cortisone acetate in doses of 5 and 10 mg per 24 hours to one rat of each pair caused significant increases in the concentration of plasma amino acids above the values for untreated animals. It is postulated that the observed change represents an extra-hepatic effect of cortisone upon protein metabolism.
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