Abstract
Summary
1. A convenient method for the isolation of allantoin from the urine of rats has been developed. 2. The carbon of sodium bicarbonate is not incorporated in the urinary allantoin of rats. This result is in accord with the fact that bicarbonate is incorporated only into position 6 of purines. 3. The carboxyl carbon of acetate is not involved in the biosynthesis of allantoin in the rat. 4. The carboxyl carbon of glycine is incorporated into position 4 of allantoin and the methylene carbon into position 5.
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