Abstract
Summary
Disproportionate sedimentation in the high speed centrifuge of hemagglutinins and infective principle of Newcastle disease virus in suspensions of infected allantoic membranes has been reported. This suggests the presence in such preparations of two hemagglutinating particles of different sizes; one of these appears to be identical with the infectious principle, the other, smaller one, according to all indications is non-infectious. The specificity of this smaller hemagglutinin has been established by hemagglutination-inhibition tests. The medium in which the virus is suspended apparently does not effect the sedimentation of hemagglutinating capacity. Experiments employing Seitz filtration have been unrevealing.
Get full access to this article
View all access options for this article.