Influence of Estradiol on P 32 Uptake by the Uterus

Abstract

Summary

1. The preferential localization of radioactive phosphorus is enhanced in the uterus of the immature rat by the administration of estradiol. 2. P³² becomes bound in the estradiol primed uterus as evidenced by the increase of P³² in the acid insoluble fraction. 3. The liver is not influenced in this process, indicating that the proliferating cells in a hormone treated target organ influence the uptake of P³². 4. The data indicate a suggested approach to the treatment of genital malignancies.