Abstract
Summary
Amphenone “B” administered either orally or parenterally, exerts an atypical trophic action on the genital tract of the ovariectomized female rat. It also effects a rapid hypertrophy of the adrenals and thyroid. These adrenal effects are lacking in the hypophysectomized rat but the uterine stimulation is unaffected either by hypophysectomy or adrenalectomy. The compound also pos sesses an acute toxicity which is characterized by marked narcosis leading to death. The maximum effective dose is approximately two-thirds of the lethal dose.
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