Abstract
Summary
Liver tissue of normal guinea pigs showed a markedly greater ability to phosphorylate substrates than tissue from ascorbic acid deficient animals. The difference in kidney tissue was less marked. The oxygen consumption of liver tissue increases noticeably in scurvy but there is no change in kidney. Adenosine triphosphatase activity of liver tissue was higher in the deficient animal as measured by the liberation of phosphate from adenosine triphosphate. Phosphorylase measurements in one group of normal animals gave higher results for both kidney and liver extracts. This was not true of muscle extracts. In the second series the results for liver were the same but a higher figure was again obtained for kidney extracts from normal animals. Aldolase activity did not seem to be lowered in scurvy.
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