Abstract
Summary
Free glutamic acid was found in all of the trained sulfathiazole, aureomycin, and penicillin-resistant strains of viridans streptococci tested, but not in the parent strains. The aureomycin and penicillin-resistant strains had also increased in sulfathiazole resistance. No glutamic acid was present in 5 trained streptomycin-resistant strains which had not increased appreciably in sulfathiazole resistance, but was found in one strain which had increased in sulfathiazole resistance. Glutamic acid appears to accompany sulfathiazole resistance regardless of how this resistance is acquired. The possible relation of the free glutamic acid to the increased resistance to sulfathiazole is discussed.
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