Abstract
Summary
Adult white rats were treated in 4 ways. In 3 of these, (a) intraperitoneal injection of 2 cc of India ink, (b) subcutaneous injection of 0.2 cc pentothal sodium per 100 g, and (c) treatment (b) followed in 20 minutes by treatment (a), blood lactic acid remained normal but body-temperature fell. In the fourth treatment, subcutaneous injection of pentothal sodium followed in 20 minutes by intraperitoneal injection of 0.5 cc ox bile, a similar fall in body-temperature occurred which was accompanied by a marked rise in blood lactic acid. The rise in blood lactic acid is taken as an indication of shock.
These experiments indicate that the hypothermia produced by the intraperitoneal injection of India ink is not secondary to shock.
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