Abstract
Summary
The guanine analogue, 5-amino-7 - hydroxy - lH - v - triazolo (d) pyrimidine (guanazolo), which has been reported to be relatively non-toxic for adult mice, wras found to be toxic for the developing chick embryo.
This was manifested by a high mortality rate, inhibition of growth, and the occurrence of developmental abnormalities. The toxic effects of guanazolo were inhibited by the simultaneous injection of guanine HCl.
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