Abstract
Summary
The antihistaminic, anticholinergic and musculotropic spasmolytic properties of the para-halogen, para-methoxy and some para-alkyl derivatives of 2-benzhydryloxy-dimethylethyl amine have been investigated. Para-substitution with methyl, ethyl and halogen atom results in an enhancement of antihistaminic activity, a decrease in acute toxicity, or both. It lowers the atropine-like action but does not produce a significant change in musculotropic spasmolytic activity.
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